Uranyl binding

A straightforward procedure ensuring the anchoring of bisphosphonate moiety onto aromatic amines has been described by Taran and co-workers (Scheme 51). In this procedure, ligands (150) were obtained in moderate yields (50%) and their uranyl-binding properties has been studied. 

Before leaving consideration of this group of compounds, mention should be made of one unusual species of this general class. Tabushi, Kobuke and Nishiya have reported a polymer-bound hexaketone, illustrated below as compound 29, which is apparently of use in binding uranyl (UO2++) ions. The polymer has, in fact, been utilized in extraction of the uranyl ion directly from seawater . 

Hsi C, Langmuir D (1985) Adsorphon of uranyl onto ferric oxyhydroxides applications of the surface complexation site-binding model. Geochim Cosmochim Acta 49 1931-1941 Ingri J, Widerlund A, Land M, Gustafsson O, Anderson P, Ohlander B (2000) Temporal variation in the fractionation of the rare earth elements in a boreal river the role of colloidal particles. Chem Geol 166 23-45... 

The removal of Pb by Brevibacterium sp strain PBZ was markedly enhanced by the presence of glucose (Simine et al. 1998). Desorption of the metal by EDTA restored the binding capacity of the cells. U(VI) could be desorped from the cell surface of B. cereus by citric acid or sodium bicarbonate with the formation of water-soluble complexes although U(VI) was strongly bound on the cell surface of the bacteria. However, uranyl in... 

Rossini, and G. Wipff, Comput. Phys. Commun., 2, 591 (2001). Do Perchlorate and Triflate Anions Bind to the Uranyl Cation in an Acidic Aqueous Medium A Combined EXAFS and Quantum Mechanical Investigation. 

The kind of information we are seeking therefore seems within reach, but is at the very limit of the performance available today from electron microscopy of uncoated and unstained biological macromolecules. Some improvements may be obtained by staining, for example with uranyl acetate. This stain binds specifically to phdsphate groups along the DNA chain without modifying the helix... 

Hotta,Y Ozeki, S. Suzuki,T. Imal, S. Ka-neko, S. (1991) Surface characterization of titanated a-Fe203. Langmuir 7 2649—2654 Howe, A.T. Gallagher, K.J. (1975) Mossbauer studies in the colloidal system P-FeOOH — P-Fe20j Structures and dehydration mechanism. J. Chem. Soc. Faraday Trans. I. 71 22-34 Hsi, C.D. Langmuir, D. (1985) Adsorption of uranyl onto ferric oxyhydroxides Application of the surface complexation site-binding model. Geochim. Cosmochim. Acta 49 1931-1941... 

Figure 11. Binding of two H2PO4 anions by the uranyl salene host 36.

Fig. 7. Fitting curves showing the contribution of two uranyl components with distinct binding energies compared with the U 4F XPS spectra of U(VI)-containing quartz samples described in Table 4. u.a., arbitary units.

Hsi, C.-K. D. Langmuir, D. 1985. Adsorption of uranyl onto ferric oxyhydroxides application of the surface complexation site-binding model. Geochimica et Cosmochimica A eta, 49,1931 -1941. 

McKinley, J. P., Zachara, J. M., Smith, S. C. Turner, G. 1995. The influence of uranyl hydrolysis and multiple site-binding reactions on adsorption of U(VI) to montmorillonite. Clays and Clay Minerals, 43, 586-598. 

Table 5 Thermodynamic Data for the Binding of Uranyl to Humic Acid58...

Probing Ca++—Phosphate Binding. Although this question has been at the center of the current investigations, little experimentation was reported on direct evidence which could be furnished by IR spectroscopy. In a brief mention of IR absorption of DPL-uranyl nitrate in nujol paste, it was concluded that indeed Ca++ interacts with the lipid phosphate group (7). Subsequently, after thermodynamic analysis of calorimetric studies with DPL dispersions in aqueous electrolyte, the same laboratory suggested the absence of direct Ca++-phosphate interaction (8). Strangely, the authors of the second work (8) failed to provide explanations for the discrepancy between this and a previous report (7). The particular predicament implies that either one of the two experiments had to be... 

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