Unexplained High and Low Serum Alkaline Phosphatase Activities

Unexplained High and Low Serum Alkaline Phosphatase Activities [Pg.179]

Physicians and laboratory scientists are occasionally confronted with isolated high or low serum alkaline phosphatase values which remain unexplained even after thorough investigation (B42). Such high or low activities may persist for prolonged periods of time (Mc3). Wilson (W28) described several members of a family with gross hyperphosphatasemia in the absence of demonstrable disease. The biochemical abnormality appeared to be inherited as an autosomal dominant trait. [Pg.179]

The clinical approach to the patient with unexplained hyperphosphatasemia is set out in Table 6. [Pg.179]

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