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Understanding gene function

Proteomics is the large-scale analysis of proteins and constitutes a valuable tool for understanding gene function. Proteomics deals mainly with protein microchaiacterization for large-scale identification of proteins and their post-translational modifications, differential-display proteomics for comparison of protein levels with potential application in a wide range of diseases and studies of protein-protein interactions using techniques such as... [Pg.14]

Naaby-Hansen, S., Waterfield, M.D., and Cramer, R., 2000, Proteomics - post-genomic cartography to understand gene function. TRENDS Pharmacol. Sci. 22 376-384. [Pg.242]

The homeobox genes represent important nodes in the genetic circuitry of development. They are nevertheless but one set of links in the chain of genetic events, and to understand their function it is necessary to determine how they are regulated and how they in turn regulate downstream genes. [Pg.109]

Brent, R., and Finley, R. L., Jr. (1997). Understanding gene and allele function with two-hybrid methods. Annu. Rev. Genet. 31, 663-704. [Pg.112]

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