Ultrahigh pressure

In this chapter I propose to exemplify the many categories of u.seful materials which depend on extreme forms of preparation and treatment, shape, mierostructure or function. My subject-matter here should also include ultrahigh pressure, but this has already been diseussed in Section 4.2.3. As techniques of preparation have steadily become more sophisticated over the last few deeades of the twentieth century, materials in extreme states have become steadily more prevalent. 

MacNair, J.E., Patel, K.D., and Jorgenson, J.W., Ultrahigh-pressure reversed-phase capillary liquid chromatography isocratic and gradient elution using columns packed with 1.0 pm particles, Anal. Chem., 71, 700, 1999. 

Mellors, J.S., Jorgenson, J.W. (2004). Use of 1.5-pm porous ethyl-bridged hybrid particles as a stationary-phase support for reversed-phase ultrahigh-pressure liquid chromatography. Anal. Chem. 76, 5441-5450. 

MDLC USING ULTRAHIGH PRESSURE LIQUID CHROMATOGRAPHY 189... 

FIGURE 8.11 Simplified diagram of the gradient ultrahigh pressure instalment. 

One of the major trends to be anticipated is greater availability of instrumentation that can be used to perform multidimensional separations at ultrahigh pressures. Some instrument makers have recently introduced LC pumps capable of operating at pressures up to 15,000 psi. As time progresses, ultrahigh pressure separations are likely to become more routine and the pressure limit of commercial instruments is likely to increase... 

Link, J.C. (2004). Development and application of gradient ultrahigh pressure liquid chromatography for separations of complex biological mixtures Dissertation, University of North Carolina, Chapel Hill. Available from UMI ProQuest Digital Dissertations, Ann Arbor, MI, AAT 3156171. 

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