Ultra-high performance liquid principles

Apart from the mentioned technological advances, the separation power and selectivity of HPLC have been drastically improved over the last years. In this context, ultra-high-performance liquid chromatography coupled with mass spectrometry (UHPLC-MS) represents a relatively new category of analytical coupled techniques that respects the principles of the classic HPLC-MS while bringing some improvements in chromatographic resolution, speed, and sensitivity. 

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