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UHTS, Ultra high-throughput screening

TEM-1 baterial enzyme y9-lactamase TNK tenecteplase t-PA tissue plasminogen activator uHTS ultra-high-throughput screening... [Pg.584]

Fig. 28 Schematic view of the Zeiss Plate Vision instrument which is state-of-the art for ultra-high throughput screening (uHTS) for drug discovery. The instrument resembles a 96-well parallel microscope the light of a excitation source (Xe-lamp or pulsed laser) is expanded to illuminate a microtiter plate. The excitation is structured into 96 channels by a mini-lens array (MLA) and focused into the well with a detection volume of < 100 nL. All 96 channels are read simultaneously by a gated, intensifed CCD. With this fast detector and the pulsed laser excitation, the instrument can be used to carry out miniaturized, 96 parallel lifetime measurements in microtiter plate format with nanosecond time resolution or time-gated detection [190]... Fig. 28 Schematic view of the Zeiss Plate Vision instrument which is state-of-the art for ultra-high throughput screening (uHTS) for drug discovery. The instrument resembles a 96-well parallel microscope the light of a excitation source (Xe-lamp or pulsed laser) is expanded to illuminate a microtiter plate. The excitation is structured into 96 channels by a mini-lens array (MLA) and focused into the well with a detection volume of < 100 nL. All 96 channels are read simultaneously by a gated, intensifed CCD. With this fast detector and the pulsed laser excitation, the instrument can be used to carry out miniaturized, 96 parallel lifetime measurements in microtiter plate format with nanosecond time resolution or time-gated detection [190]...
Ultra-high-throughput screening (uHTS) 596 Ultrasonic spectroscopy... [Pg.1884]

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High screen

High screening

High-Throughput Screening

High-throughput

Screen high-throughput

Ultra-high

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