Type I Cytokine Family

Type II cytokines include IL-10, IL-19, IL-20, IL-22, and interferons (IFN-a, - 3, -e, -k, -co, -6, -x and -y). Functions of this group include induction of cellular antiviral states, modulation of inflammatory responses, inhibition or 

Stimulation of cell growth, and production or inhibition of apoptosis, as well as affecting many immune mechanisms (Renauld, 2003 Pestka et al., 2004). Notably, IL-10 is a potent anti-inflammatory, immunomodulatory cytokine. The IFN system is an important contributor to innate immunity with IFN-y serving as a potent pro-inflammatory cytokine. The type II cytokine family is also comprised of both ThI and Th2 cytokines IFN-y is a ThI cytokine while IL-IO is a Th2 cytokine. 

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