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Tumor necrosis factor-alpha autoimmunity

Finally, antibodies such as adalimumab (Humira) and infliximab (Remicade) have been developed that bind directly to tumor necrosis factor alpha (TNF-alpha), thereby preventing this cytokine from causing damage to joints and other tissues. These anti-TNF-alpha drugs are therefore helpful in autoimmune diseases such as rheumatoid arthritis their pharmacology is addressed in more detail in Chapter 16. [Pg.599]

Recombinant human soluble tumor necrosis factor-alpha (TNF-a) receptor protein Enbrel (etanercept) Autoimmune diseases Amgen-Wyeth 4.5... [Pg.298]

Vermeire S, Noman M, Van Assche G, Baert F, Van Steen K, Esters N, Joossens S, Bossuyt X, Rutgeerts P (2003) Autoimmunity associated with anti-tumor necrosis factor alpha treatment in Crohn s disease a prospective cohort study. Gastroenterology, 125 32-39. [Pg.319]

TNF-a Tumor necrosis factor alpha Inhibits tumor cells mediates immune response against bacterial infection induces septic shock, autoimmune diseases, rheumatoid arthritis, inflammation, and diabetes... [Pg.1211]

Jacob CO. Tumor necrosis factor alpha in autoimmunity pretty girl or old witch. Immunol Today 1992 13 122-125. [Pg.211]

Jacob CO, McDevitt HO. Tumor necrosis factor-alpha in autoimmune lupus nephritis. Nature 1988 331 356-358. [Pg.211]

See other pages where Tumor necrosis factor-alpha autoimmunity is mentioned: [Pg.204]    [Pg.71]    [Pg.229]    [Pg.122]    [Pg.221]    [Pg.182]   
See also in sourсe #XX -- [ Pg.487 ]



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