Tropane alkaloids from Duboisia myoporoides

Shukla YN, Thakur RS (1992) Tropane alkaloids from Duboisia myoporoides. Phytochemistry 31 4389-4390... 

Gerrard AW (1880) Tropane alkaloids of Duboisia myoporoides. Pharm J 11 383 Ghani A (1985) Cuscohygrine from some solanaceous plants. Ind J Pharm Sci 47 127-129 Ghani A, Evans WC, Woolley VA (1972) Alkaloids of Hyoscyamus species. Bangladesh Pharmac J 1 12-14... 

The cell and tissue culture of the major tropane alkaloid-producing species does not apparently offer any special problems. The regeneration of plantlets from callus and tissue cultures seems to be routine (286,307,309,323,325,332,350-352). Plants have also been regenerated from protoplasts of Atropa belladonna (353), Duboisia myoporoides (354), and Hyoscyamus muticus (355,356). Cryopreservation has been reported for Anisodus and Datura species (349,357). 

If any Tl-type alkaloids occur in a specific taxon, there may be present between only one metabolite (e.g., Anthocercis littorea) and up to six congeners of this type [e.g., Cyphanthera albicans, Hyoscyamus pusillus (4) Datura inoxia (5) Duboisia myoporoides (6)]. Such alkaloids are normally accompanied by one or more different types of tropane alkaloids (T3 - T6 Schizanthoideae T7-D), e.g., alkaloid extracts obtained from the leaves of Duboisia leichhardtii contained hyoscyamine as the principal component accompanied by minor congeners like scopolamine (hyoscine) as well as different Tl-type esters (e.g., butropine, valtropine). Both latter... 

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