Tritiation recoil labeling

For tritiating heterocyclic compounds the recoil method has been used to label nicotinic acid (l)11-18 and also reserpine.14,15... [Pg.139]

I he damage from the recoil tracks of an individual tritium atom may have an effect on the labeled molecules it produces only in the liquid and solid phases, where there is considerable restraint on the motion of the tritiated molecules and radicals at the end of the track. These species can interact with fragments produced by radiation... [Pg.222]

A method for preparing tritium-labelled oligosaccharides of hyaluronic acid has used the Wilzbach recoil technique the tritiated oligosaccharides are of potential use in studies of the mechanism of hyaluronidases. A four-fold helical form of hyaluronic acid has been detected using the data from fibre-... [Pg.290]

Treatment of hyaluronic acid with hydrazine removed some of the A -acetyl groups, which were reconstituted on reacetylation with tritiated acetic anhydride the tritiated mucopolysaccharide was used as a substrate in a semimicro assay for hyaluronidase. Tritium-labelled hyaluronic acid, labelled by the tritium-recoil technique, has been treated with j8-D-glucuronidase to yield tritiated oligosaccharides containing terminal, non-reducing 2-acetamido-2-deoxy-j3-D-glucopyranosyl residues. ... [Pg.469]

Big Chemical Encyclopedia