Triphosphopyridine nucleotide, synthesis

A. Kornberg (1950). Enzymatic synthesis of triphosphopyridine nucleotide. J. Biol. Chem., 182, 805-813. 

Enzymatic synthesis of triphosphopyridine nucleotide. J. biol. Chem. 

Until recently little information was available concerning the mechanism of long-chain fatty acid synthesis in adipose tissue. Martin et al. (1961) have isolated and partially purified a soluble enzyme system from rat epi-didymal adipose tissue that synthesizes long-chain fatty acids. When acetyl CoA, malonyl CoA, and reduced triphosphopyridine nucleotide are used as substrates, the major product of the reaction is palmitic acid. 

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