Trimethyltin chloride, toxicity

IBT. 1976b. Acute vapor inhalation toxicity study with trimethyltin chloride in rats. Report to M and T Chemicals, Inc., Rahway, NJ, by Industrial Bio-Test Laboratories, Inc., Northbrook, IL. IBT No. 8562-08285. 

Paule MG, Slikker W Jr. 1984. Developmental toxicity of prenatal trimethyltin chloride (TMT) exposure in the rat. Teratology 29 504. 

Caution. Because of its toxicity and volatility, care should be taken to avoid inhalation of trimetyltin chloride (chlorotrimethylstannane) or contact of its solutions with the skin. Cyclopentadienyltrimethylstannane has a pungent odor and may be assumed to possess toxic properties similar to those of trimethyltin chloride. 

TRIMETHYLTIN HYDRIDE (1631 -73-8) (CH3)3SiCF=CF2 High acute toxicity. Reacts with water, producing highly flammable hydrogen gas. Violent reaction with oxidizers. See also trimethyltin chloride. 

Trimethyltin chloride is highly toxic by all routes of exposure. 

Because of its high acute toxicity, trimethyltin chloride should be handled using the "basic prudent practices" of Chapter 5.C, supplemented by additional precautions for work with compounds of high acute toxicity (Chapter 5.D). Other alkyltin compounds should be handled using the "basic prudent practices" of Chapter 5.C. 

Caution. Tetramethyltin and trimethyltin chloride are very toxic and volatile. All transformations are therefore to be performed under a hood. 

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