Trimethylamine, compound with

Notable examples of general synthetic procedures in Volume 47 include the synthesis of aromatic aldehydes (from dichloro-methyl methyl ether), aliphatic aldehydes (from alkyl halides and trimethylamine oxide and by oxidation of alcohols using dimethyl sulfoxide, dicyclohexylcarbodiimide, and pyridinum trifluoro-acetate the latter method is particularly useful since the conditions are so mild), carbethoxycycloalkanones (from sodium hydride, diethyl carbonate, and the cycloalkanone), m-dialkylbenzenes (from the />-isomer by isomerization with hydrogen fluoride and boron trifluoride), and the deamination of amines (by conversion to the nitrosoamide and thermolysis to the ester). Other general methods are represented by the synthesis of 1 J-difluoroolefins (from sodium chlorodifluoroacetate, triphenyl phosphine, and an aldehyde or ketone), the nitration of aromatic rings (with ni-tronium tetrafluoroborate), the reductive methylation of aromatic nitro compounds (with formaldehyde and hydrogen), the synthesis of dialkyl ketones (from carboxylic acids and iron powder), and the preparation of 1-substituted cyclopropanols (from the condensation of a 1,3-dichloro-2-propanol derivative and ethyl-... 

This enzyme system catalyzes the oxidation of various nitrogen-, sulfur -, and phosphorus-containing compounds, which tend to be nucleophilic, although compounds with an anionic group are not substrates. For example, the N-oxidation of trimethylamine (Fig. 4.19) is catalyzed by this enzyme, but also the hydroxylation of secondary amines, imines, and arylamines and the oxidation of hydroxylamines and hydrazines ... 

Boron fluoride, for catalysis, 1 23 compound with hexamethyldi-silazane, 5 58 high-purity, 1 2l Boron fluoride-trimethylamine, 5 26... 

Trimetaphosphimic acid, 6 79 Trimethylamine, coordination compounds with boron fluoride and chloride, 5 26, 27 purification of, 2 159 Trimethylamine-sulfur dioxide, 2 159... 

The addition compound of trimethylamine and monobromo-borane has been prepared by reaction of trimethylamine-borane with either bromine or boron tribromide,4 but an excess of either reagent gives further bromination. Hydrogen bromide, however, gives only the monobromo derivative, even when added in excess. The synthesis is similar to that of trimethylamine-... 

Ref 93). Extreme caution should be used in reducing any fluorinated compound with LiAlH. Violent reactions have been observed with two different fluoro compounds (Refs 76 St 95). Excess trimethylamine, NMe, reacts with an ethereal - solution of LiAlH in vacuo at -50SC to form a white addition compound which js slightly soluble in ether, insoluble in benzene, and spontaneously flammable in air (Ref 98a) Magnesium perchlorate may be used as a drying... 

Basic groups giving an anion exchange resin can be inserted by first combining with chloromethylether, in the presence of a catalyst such as aluminium chloride. The product, when treated with trimethylamine, yields a quaternary ammonium compound with basic properties such as shown below ... 

BC1j-(CH3)3N Boron chloride-trimethylamine, 5 27 BF3 Boron fluoride, 1 21, 23 compound with hexamethyl-... 

BBrj Boron bromide, 3 27, 29 BCls Boron chloride, 3 27, 28, 29 BCls CCHslsN Boron chloride-trimethylamine, 6 27 BCI3-PCI5 Boron chloride, compound with phosphorus (V) chloride, 7 79... 

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