Triiodomethane iodoform

Fluorodibromo- [19] and fluorodiiodomethane [20] each react to form a fluorohalocarbene. Chlorodiiodomethane and triiodomethane (iodoform) have likewise been subjected to phase transfer conditions and have yielded the expected car-benes [21 ]. On the other hand, chlorodifluoromethane (Freon 22) did not yield the desired difluorocarbene and it appears that no attempt to prepare either chlorobromo-... 

Iodine as such finds few uses but a solution in alcohol and water, also containing potassium iodide ( tincture of iodine was commonly used as an antiseptic for cuts and wounds, but had rather an irritant action. Iodoform (triiodomethane), CHI3, is also an antiseptic, but newer compounds of iodine are now in use. Silver iodide, like silver bromide, is extensively used in the photographic industry. 

In the iodoform reaction, a triiodomethyl ketone reacts with aqueous NaOH to yield a carboxylate ion and iodoform (triiodomethane). Propose a mechanism for this reaction. 

CondChemDict (1971), p 573 Iodoform or Triiodomethane, CHI3 mw 393.78 yellow leaflets, mp 115°, bp 260° (decomp), d 4.08 sol in w, ale, eth chlf. Prepd by heating acetone (or methanol) with iodine in the presence of alkali. There is considerable confusion in the literature whether iodoform is an explosive. Beilstein (Ref 1), Sax (Ref 2), and CA 1947—1971 do not mention any explosive properties. Ref 3 states that iodoform decomps violently at 400°F. Friction makes a mixt of CHI3+AgN03 decomp explosively (Ref 1)... 

Triiodobenzenediazonium nitrate, 2077 Triiodocyclopropenium iodide, 1335 Triiodomethane, see Iodoform, 0375... 

Iodoform. Triiodomethane. CHIy mol wt 393.78. C 3.05%. H 0.26%, I 96.69%. Prepn from acetone, sodium hypochlorite, potassium iodide, and sodium hydroxide Glass, Quart. J. Pharm. Pharmacol. 8, 351 (1935) from chloroform + methyl iodide Soroos, Hinkamp, J. Am. Chem. Soc. 67, 1642 (1945) by electrolysis Glasstone, Ind. Cheat. 7, 315 (1931). Description of the iodofoim reaction Seelye, Turney, J. Chem. Ed. 36, 572 (1959). 

AI3-52396 Carbon triiodide CCRIS 346 Dezinfekt V EINECS 200-874-5 HSDB 4099 Iodoform Jodoform Methane, triiodo- NCI-C04568 NSC 26251 Triiodomethane Trijodmethane, Used as a topical anti-infective and disinfectant. Yellow crystals mp = 119° bp B 218° d = 4,008 insoluble in H2O, more soluble in organic solvents LDso (rat orl) = 355 mg/kg. Alfa Aesar Allchem ind, ClarianI Corp, Lancaster Synthesis Co. Molekula Fine Chemicals Walton Pharm. 

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