Trichloroacetic acid hyperpigmentation

CoteUessa C, Peris K, Eaignoli MC, Mordenti C, Giacomello RS, Chimenti S (2003) Microabrasion versus microabrasion followed by 15% trichloroacetic acid for treatment of cutaneous hyperpigmentations in adult females. Dermatol Suig 29(4) 352-356... 

There are hardly any studies on trichloroacetic acid alone for chemical peeling in Asian patients. In a study of 15 patients from Iraq, a medium-depth chemical peel using a combination of Jessner s solution followed by the application of 35% trichloroacetic acid was performed for up to three sessions for acne scars. This medium-depth chemical peel was found to be a safe and effective way of treating patients of dark complexion. The side effects noted were transient postin-flammatory hyperpigmentation [14]. 

For the treatment of melasma (symmetric progressive hyperpigmentation of the facial skin), a study was done comparing modified Jessner s solution and 15 % trichloroacetic acid (TCA) versus 15 % TCA alone [318], Modified Jessner s solution (see above) was found to be useful as an adjuvant treatment with 15 % TCA [318]. 

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