Trichloroacetic acid contraindications

Pregnancy Agents contraindicated in pregnancy include podofilox, fluorouracil, and podophyllin. Imiquimod is not approved for use in pregnancy, although it has been considered after signed consent has been obtained. Bichloroacetic and trichloroacetic acid have been used without problems. Ablative therapy is also a viable option. 

Tryptophan is another amino acid that tends to bind with protein it is also sensitive to the deproteinization process. The use of sulfosalicylic acid (SSA) in particular is contraindicated. Trichloroacetic acid, on the other hand, leaves tryptophan unaffected. 

If there were a secret to safety, it would lie in a thorough knowledge and understanding of this type of treatment. For doctors to give patients a wide range of choice, they must know how to use at least the three main types of conventional peels correctly alpha-hydroxy acids (AHAs), trichloroacetic acid (TCA) and phenol (for phenol, the doctor should at least know how to apply it locally). For each type of peel, the doctor must be perfectly acquainted with its indications, results, limitations and complications to be able to choose the right product for a given patient and to be able to apply it correctly. The patient should be informed of alternative techniques, their possibilities, contraindications, side-effects and cost. 

Trichloroacetic acid (TCA) (Figs. 20.5 and 20.6) The 60% TCA peel has produced similar results in patients in whom phenol is contraindicated or undesired. TCA is a keratocoagulant. TCA may be applied more rapidly than phenol, but it is more likely to produce hypertrophic scarring (Fig. 20.6) [21]. 

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