Trichloro methane

Chloroform Trichloro methane 192 CHCh Methyl isopropyl ether 104 C4Hi 0... 

A mixture of 2.3 parts of 2-(4-methoxyphenyl)ethyl methanesulfonate, 4.9 parts of 1-[(4-fluorophenyOmethyl] -N-(4-piperidinyl)-1H-benzimidazol-2-amine dihydrobromide, 3.2 parts of sodium carbonate, 0.1 part of potassium iodide and 90 parts of N,N-dimethylformamide is stirred overnight at 70°C. The reaction mixture is poured onto water. The product is extracted with methylbenzene. The extract is washed with water,dried, filtered and evaporated. The residue is purified by column-chromatography over silica gel using a mixture of trichloro-methane and methanol (98 2 by volume) as eluent. The pure fractions are collected and the eluent is evaporated. The residue is crystallized from 2,2 -oxybispropane, yielding 2.2 parts (48%) of 1 -(4-fluorophenvlmethyl)-N-[1 - [2-(4-methoxvphenyl)ethvl] -4-piperidinyl] -1H-benzlmidazol-2-amine MP 149.1°C. 

Zietlow, J. P.. F. F. Cleveland, and A. G. Meister Substituted methanes. III. Raman spectra, assignments, and force constants for some trichloro-methanes. J. chem. Phys. 18, 1076—1080 (1950). 

Fig. 7-1. Flammett correlation between ir-values and the logarithms of the relative rate constants of the Sn2 alkylation reaction of substituted pyridinium iV-phenolate betaines with iodomethane in trichloro-methane at 25 °C [16].

Related to Diels-Alder [2 + 2]cycloadditions are 1,3-dipolar cycloadditions, which are known to be far less solvent-dependent cf. Eq. (5-44) in Section 5.3.3. Nagai et al [169] found that the 1,3-dipolar cycloaddition reaction of diazo-diphenylmethane to tetracyanoethene (TONE) is an exception it is 180 times faster in nonbasic trichloro-methane than in the EPD solvent 1,2-dimethoxyethane cf. Eq. (7-25). The second-order... 

There are some serious limitations in the determination of Z values. First, Z values can only be obtained by direct measurement over the solvent range trichloro-methane (Z = 63.2 kcal/mol) to 70 30 cL/L ethanol/water (Z = 86.4 kcal/mol). In highly polar solvents, the long-wavelength charge-transfer band moves to such short wavelengths that it cannot be observed underneath the much stronger n n absorption band of the pyridinium ion. Therefore, the Z value for water was obtained by extra-... 

The substitution reactions can continue, replacing the remaining hydrogen atoms in the methane molecule one at a time. The products are dichloromethane, trichloromethane, and tetrachloromethane. Trichloro-methane is commonly known as chloroform, which was once used as an anesthetic. The common name for tetrachloromethane is carbon tetrachloride, which for many years was commonly used as a solvent. 

A stoichiometric relation is merely a representation of the proportion between chemical species. To illustrate, consider the chlorination of metiiane to produce trichloro methane. When methane and chlorine are contacted in a reactor, the following chemical reactions occur ... 

To relate the amount of trichloro methane (the desirable product) generated to the reactants (methane and chlorine), we add the first three reactions to obtain the following stoichiometric relation ... 

In primary synthesis 2-perimidinamines (660) can be prepared from the naphthalene diamine with bromocyanogen or cyanamide (Scheme 106). 2-Anilino derivatives have been obtained in reactions with aryl isothiocyanates. 2-iV,7V-Dimethylamino derivatives (662) have been obtained via the alkylated amine (661) using dimethylamino(trichloro)methane. Nucleophilic substitution by amine readily occurs in the 2-position when carrying a halo, sulfenyl, or sulfonyl substituent <81RCR816>. 

Compute the panial molar enthalpies of trichloro-methane and ethanol in their mixtures at over the whole composition range. 

The phenyl-trichloro methane is isolated and reacted with benzene in the presence of AICI3. 

Trichloro methane Methyl trichloride CHCI3 Dibromo methane Methyl dibromide CH2Br2 Tetrachloro methane Methyl tetrachloride Carbon tetrachloride CCI4... 

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