Trichilia trifolia

Three new dolabellanes (24-26) were isolated from the wood of Trichilia trifolia (family Meliaceae, mahogany family ) collected in Yucatan, Mexico... 

Fig. 2 Dolabellanes (24-26) isolated from the plant Trichilia trifolia (2000). Dolabellane (27) from the liverwort Pleurozia gigantea...

Other studies show the presence of a diversity of compounds other than limonoids as defenses in the tissues of Meliaceae. Woody tissues of Trichilia trifolia afforded three novel dolabellanes with flexible Curing structures. These substances were very active antifeedants in the Sitophilus bioassay (Ramirez et al., 2000). T. martiana seeds yielded large amounts of 2-((Z,Z)-6,9-heptadecadienyl)furan. T. hirta and T. americana bark have yielded novel steroids by insect bioassay-guided isolation and application of a nanoprobe nuclear magnetic resonance (NMR) technique for structure elucidation (Chaurest etal.,1996). Compounds isolated included hydroxyandrosta-l,4-diene-3,16-dione (Fig. 1.4) and derivatives. However, studies by Wheeler et al. (2001) suggest that other unidentified compounds may also be... 

Ramirez, M- ., Toscano, R Arnason, J., Omar, S., Cerda-Garcia-Rojas, . M. and Mata, R. (2000). Structure, conformation and absolute configuration of new antifeedant dolabellanes from Trichilia trifolia. Tetrahedron 56 5085-5091. 

This group, to which limonin belongs, is characteristic of the Rutaceae and rare in Meliaceae. Obacunol (59) occurs in Lovoa trichiliodes (7) and in Carapa procera 183 dihydronomilin acetate (60) in Xylocarpus granatum 16, 142) and 6P-acetoxyobacunol acetate (61) in Trichilia trifolia. The stereochemistry of the 6-substituent in this compound is very unusual, but appears to be correct 201). 

Taylor, D. R. New Limonoids from Trichilia trifolia (Meliaceae). Revista Latinoamericana de Quimica 2, 87 (1971). Chemical Abstracts 75, 129969 a (1971). Zanno, P. R., I. Miura, K. Nakanishi, and D. L. Elder Structure of the Insect Phagorepellent Azadirachtin. Application of PRFT/CWD Carbon-13 Nuclear Magnetic Resonance. J. Amer. Chem. Soc. 97, 1975 (1975). 

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