Triazole-Substituted Oleanolic Acid Derivatives as Anticancer Agents

3-Triazole-Substituted Oleanolic Acid Derivatives as Anticancer Agents 

From the biological studies, compound 54 is found to be a potent apoptosis inducer in HT1080 cells and thus can serve as a promising lead candidate for further studies. 

There are several recent reports in the Hterature on 1,2,3-triazole-linked substituted dihydrofurocoumarin hybrids [82], carbanucleoside [83], berberine derivatives [84], dehydroabietic acid variants [85], carnosic acid, and carnosol analogs [86] showing anticancer activity in vitro and are in early stages of drug discovery. 

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S 1,2,3-Triazole-Substituted Oleanolic Acid Derivatives as Anticancer Agents... 

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