Triazole Polymers

Poly( 1,2,4-triazole)s (PT)s are heterocyclic polymers, which were first synthesized by the reaction of bistetrazoles and a bisimidoyl chloride. Meanwhile, several different reaction pathways have been developed to prepare these polymers.  

Suitable monomers are summarized in Table 9.1. 1,2,4-Triazole is a white to pale yellow solid with a melting point of 120°C. Synonyms are pyrrodiazole, IH-1,2,4-triazole, and 5-triazole. This compound should not be confused with a sulfanilamide compound that is addressed as triazole. In contrast to a triazole, a triazin refers to a 6-membered ring with three nitrogen atoms. 1,2,4-Triazole is used for the synthesis of agrochemicals, pharmaceutical substances, hydraulic fluids, and photochemical products. Both 1,2,4-triazole and 1,2,4-triazole are effective solvents for proton conducting electrol54es.  

4-Triazole 3,5-Dimethyl-1,2,4-triazole 3-Amino-1,2,4-triazole Benzotriazole 1-Vinyl- 1,2,4-triazole 

Further, the feasibility of poly(ethylene glycolj-supported azide cycloadditions towards acetylene compounds has been demonstrated. A systematic study on the behavior of these kind of azides towards acetylenes, ethylenes and the cyano group has been published.  

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There are essentially no registered trademarks concerning triazole polymers, at least in the United States. In contrast, there are some trademarks with regard to agricultural products. Tradenames appearing in the references are shown in Table 9.4. 

A modified electrode using a functionalized triazole polymer film may serve as electrochemical sensor for L-methionine [89]. There, a glassy carbon electrode is modified with an electropolymerized film of 3-amino-5-mercapto-l,2,4-triazole. The sensor works at physiological pH. L-Methionine is an essential amino acid which occurs in human blood plasma, serum, and urine. An abnormal concentration of L-Methionine may cause coronary artery disease. 

Abshire CJ, Marvel CS. Some oxadiazole and triazole polymers. Makromol Chem 1961 44-6 388-97. 

Revin SB, John SA. Selective and sensitive electrochemical sensor for 1-methionine at physiological ph using functionalized triazole polymer film modified electrode. Electroanalysis 2012 24(6) 1277-83. 

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