Treatment of exposure

There is no specific antidote for acrolein exposure. Treatment of exposure should be directed at the control of symptoms and the clinical condition. Most of the harmful effects of acrolein result from its highly irritating and corrosive properties. 

This section will describe clinical practice and research concerning methods for reducing toxic effects of exposure to methyl parathion. However, because some of the treatments discussed may be experimental and unproven, this section should not be used as a guide for treatment of exposures to methyl parathion. When specific exposures have occurred, poison control centers and medical toxicologists should be... 

Young WN, Tebrock HA. 1958. The treatment of exposure to thorium and uranium with a chelating agent and supportive measures. Ind Med Surg (Annual Meeting) 27 229-232. 

Holmes, J.H., Gaon, M., Coulson, E. 1958. Treatment of exposures to anticholinesterase agents with 2-PAM. Semi-Annual Progress Report, Sept. 1957-March 1958, Contract No. DA-18-108-cml-5586. 

Unithiol and succimer increase urine mercury excretion following acute or chronic elemental mercury inhalation, but the impact of such treatment on clinical outcome is unknown. Dimercaprol has been shown to redistribute mercury to the central nervous system from other tissue sites, and since the brain is a key target organ, dimercaprol should not be used in treatment of exposure to elemental or organic mercury. Limited data suggest that succimer, unithiol, and N- acetyl-L-cysteine (NAC) may enhance body clearance of methylmercury. 

First-aid practices for the treatment of exposure to nitric acid should be obtained from a current version of the Material Safety Data Sheet or other appropriate safety literature. 

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