Transition metal allenyl complexes synthesis

Homometallic and Heterometallic Transition Metal Allenyl Complexes Synthesis,... 

Doherty, Simon, Corrigan, John P., Carty, Arthur J., and Sappa, Enrico, Homometallic and Heterometallic Transition Metal Allenyl Complexes Synthesis, Structure, and Reactivity. 

Homometallic and heterometallic transition metal-allenyl complexes synthesis, structure, and reactivity ... 

Grigg and co-workers have used a sequential, one-pot Petasis borono-Mannich reaction with either Pd(0)-catalyzed carbonylative amination cyclization or Pd(0)-cat-alyzed allenylation/amination cyclization (Scheme 7.7) [46]. The overall approach results in the formation of a-amino acid derivatives of isoindolone 25 and 4-methylene-3,4 -dihydroisoquinoline 26. While this is the only reported example of a combination of a Petasis borono-Mannich reaction with a Pd(0)using other Pd(0) or transition metal catalyzed reactions is a very attractive strategy for the synthesis of complex molecules or combinatorial libraries. 

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