Transition from batch to continuous processing

TRANSITION FROM BATCH TO CONTINUOUS PROCESSING 

For mos sulfonates, batch processing has always been, and probably will continue td be, the standard preparative procedure. This is especially true 

Dimethyl Ether. The specialty methylating agent, dimethyl sulfate, was originally made in batches in two steps  

Over-all yield was fair, but the final produc required a second distillation to achieve reasonable purity, spent acid was obtained as a by-product, and the operation as a whole was laborious. 

It has long been known that dimethyl ether and SOs form dimethyl sulfate as follows  

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The Microreactor a systematic and efficient tool for the transition from Batch to Continuous Process Chem. Eng. Res. Des., 84 (5), 363-369. 

VIII. TRANSITION FROM BATCH TO CONTINUOUS PROCESSING... 

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