Transformation diverse metal

We start with butane-2,3-dione dioxime, more commonly known as dimethylglyoxime (dmg). It is a classic reagent for the analysis of NP, the green aqueous solution of metal ions transforming into a vibrantly red precipitate of Ni(dmg)2 complex it is one of the stars of the show in Ponikvar and Liebman s analytical chemistry chapter in the current volume. Here the stereochemistry is well-established and well-known—both OH groups are found on the same side as their adjacent CH3 group on the butanedione backbone. There have been several measurements of the enthalpy of formation of this species for which we take the one associated with this inorganic analytical chemistry application, i.e. with diverse metal complexes and chelates . 

Direct sp C-H bond functionalization has attracted much attention in the past few decades, which presents high efficient, atom-economical pathways to construct new functional groups from easily available chemicals. Most of present C-H bond transformations need to use expensive metals, such as palladium, rhodium, iridium, etc. [13]. Compared to these metals, silver is relatively economically attractive and has been proved highly efficient for C-H activation in recent years, in particular, silver-mediated sp C-H bond transformation. Diverse Ag complexes exhibited... 

Few methodologies have either the diversity of synthetic transformations or the high level of product selectivity as catalytic reactions with the intermediate involvement of metal carbenes [ 1-5]. They provide synthetic opportunities that are clearly demonstrated in the preparation of the antidepressant sertraline (1)... 

Enzyme-mediated oxidation reactions offer highly diverse options for the modification of existing functional groups as well as for the introduction of novel function in chiral catalysis. Biooxidations often enable us to obtain complementary solutions to metal-assisted transformations and organocatalysis and are considered one of the important strategies of green chemistry . 

To our knowledge, no thematic volumes devoted solely to metal-catalyzed reductive C-C bond formation have been assembled. For the first time, in this issue of Topics in Current Chemistry, we present a compilation of monographs from several leaders in this burgeoning area of research. This collection of reviews serves to capture the diversity of catalytic reductive C-C couplings presently available and, in turn, the remarkable range of reactivity embodied by such transformations. There is no indication that this field has reached its zenith and it is the hope of the present author that this volume will fuel further progress. 

A tremendous number of transformations of allenes have been reported owing to their high jt-coordination ability towards transition metals. Among them, intramolecular cycloaddition reactions of allenes, in particular, appear to be a practical means of carbon-carbon bond formation in a complicated system. The allenic moiety, however, should be precisely designed for the synthetic purpose of more complex frameworks. A formidable challenge is the synthesis of diversely functionalized allenes of high chemical and/or enantiomerical purity. 

The exploration of DoM chemistry in haloheteroaromatics is valuable for two reasons (a) halo derivatives can be readily prepared from acessible amino, hydroxy, and, at times, unsubstituted systems, and (b) halogens can be subsequently induced to undergo a variety of funcionalizations via addition-elimination, metal-halogen exchange, SRN1, and cross coupling reactions. Some of these transformations are more facile than in the aromatic series. Thus, DoM tactics may lead to diverse substituted heteroaromatics, which can be difficult to obtain by more classical means. 

The past four years have been characterized by more and more diverse applications of aqueous organometallic chemistry for the synthesis of fine chemicals. Useful classical transformations have been realized in aqueous solutions. The recycle of the transition metal catalyst has sometimes been possible, but the main importance at this early stage lies in the reactions themselves. 

Intramolecular cyclopropanation reactions of alkenyl diazo carbonyl compounds are among the most useful catalytic metal carbene transformations, and the diversity of their applications for organic syntheses is substantial [7,10,24,84]. Their catalytic asymmetric reactions, however, have only recently been reported. An early application of the Aratani catalyst 2 (A = PhCH2) to... 

---