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Ultrasound transdermal drug delivery

Lavon A, Kost J. Ultrasound and transdermal drug delivery. Drug Discov Today 2004 9 670-676. [Pg.266]

Levy, D., et al. 1989. Effect of ultrasound on transdermal drug delivery to rats and guinea pigs. J Clin Invest 83 2074. [Pg.328]

Kost, et al. 1988. Ultrasound enhancement of transdermal drug delivery. Cambridge, MA Massachusetts Institute of Technology. US Patent 4,767,402. [Pg.328]

Bommannan, D., et al. 1992. Sonophoresis. I. The use of high-frequency ultrasound to enhance transdermal drug delivery. Pharm Res 9 559. [Pg.328]

Johnson, M.E., et al. 1996. Synergistic effects of chemical enhancers and therapeutic ultrasound on transdermal drug delivery. J Pharm Sci 85 670. [Pg.328]

Mitragotri, S. Blankschtein, D. Langer, R. Sonophoresis enhanced transdermal drug delivery by application of ultrasound. In Encyclopedia of Pharmaceutical Tech- 112. nology, 1st Ed. Swarbrick, J., Boylan, J.C., Eds. Marcel Dekker, Inc. New York, 1996 14, 103-122. [Pg.2756]

Over the last 20 years, transdermal route of delivery has been considered as a means for systemic drug administration. Over this period, sonophoresis has been attempted to enhance systemic transdermal delivery. Levy et al. ° showed that 3-5 min of ultrasound exposure (IMHz, 1.5W/cm ) increased transdermal permeation of mannitol and physostigmine across hairless rat skin in vivo by up to 15-fold. They also reported that the lag time typically associated with transdermal drug delivery was nearly-completely eliminated after exposure to ultrasound. ° ... [Pg.3834]

Kost, J. Langer, R. Ultrasound-mediated transdermal drug delivery. In Topical Drug Bioavailability, Bioequivalence, and Penetration Shah, V.P., Maibach, H.I. Eds. Plennum New York, 1993 91-103. [Pg.3841]

Mechanism of enhancement of transdermal drug delivery by low-frequency ultrasound... [Pg.246]

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See also in sourсe #XX -- [ Pg.317 , Pg.318 , Pg.319 , Pg.320 , Pg.321 , Pg.322 , Pg.323 , Pg.324 , Pg.325 , Pg.326 ]



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