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Transcriptional Regulators as Diagnostic Metabolite Sensors for Screening

Transcriptional Regulators as Diagnostic Metabolite Sensors for Screening [Pg.377]

The genetically encoded biosensors hitherto applied to C. glutamicum strain development are the transcriptional regulators Lrp [168] and the L-lysine regulator LysG [39]. The transcriptional activator LysG senses high intracellular [Pg.377]

Quantitation of intraoeriiuiai i-iysine Direct (juantitation of the i-iysino as a proxy for product titers prodrret titer in the medium [Pg.378]

Biosensors or T ranscriptional Riboswitches Auxanographic At-line robotic [Pg.378]

Detection -35 mM (LysG) 25-100 M (BSRS) MNIimolar range Wide dynamic [Pg.378]



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A transcriptional regulation

A-SCREEN

Regulation transcription

Screening for

Transcriptional regulation

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