Trans -geranyl acetone

From tobacco, Schumacher and Heckman have isolated trans-actinidiolide (325), the c/s-isomer having been isolated previously. A synthesis from geranyl-acetone was effected, the essential step being the oxidation of the cyclized compound (326) with permanganate. "" Isoe et al. have extended their successful... 

The stems of E. arvense contain volatile oil with 25 identified compounds. The major constituents include hexahydrofamesyl acetone, geranyl acetone, thymol, and trans-phytol. ... 

Oxidation of 1,5-dienes to c -tetiahydrofurandiols was accomplished with RuO /aq. Na(10 )/acetone-EtOAc thus 2,5-dimethyl-1,5-hexadiene gave tetrahydrofurandiol, geranyl acetate yielded cw-tetrahydrofurandiol, and trans, tra 5-2,6-dimethyl-2,6-octadiene-l,8-diol diacetate (1) gave tetrahydrofuran ketol diacetate (2) (Fig. 3.12 cf. mech. Ch. 1) [174],... 

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