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Toxins modified agents

Asparagine is unique as an acceptor amino acid for ADP-ribosylation by C3-like transferases (Sekine et ai, 1989). In contrast, pertussis toxin modifies cysteine residues, and cholera toxin and C. botulinum C2 toxin specifically ADP-ribosylate arginine residues (for details see the relevant chapters). The ADP-ribose-asparagine bond formed by C3-like transferases is stable towards neutral hydroxyl-amine [0.5 M, 2h) and mercury ions (2m/Vl, 1 h), whereas cysteine and arginine-specific ADP-ribosylation, respectively, are sensitive towards these agents (Aktories ef a/., 1988a). [Pg.66]

Cyanide Phosgene Mustard Nerve Agents Aerosols Chemical Weapon Substance P Neurokinin A Saxitoxin Ricin Botulinum Toxin Biological and Toxin Modified/tailored bacteria and viruses Weapons Convention Bacteria Viruses Rickettsia Anthrax Plague Tularemia... [Pg.641]

Nomenclature. The terms active agent and pharmacon designate substances that are capable of modifying life processes irrespective of whether the effects elicited may benefit or harm the organisms concerned. By this definition, a toxin is also a pharmacon. Taken in a narrower sense, a pharmacon means a substance that is used for therapeutic purposes. An unequivocal term for such a substance is medicinal drug. [Pg.333]

Toxins, bioregulators, synthetic viruses, or traditional agents modified to enhance virulence... [Pg.274]

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See also in sourсe #XX -- [ Pg.462 ]



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Modified agents

Modifying agents

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