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Toxicity general approach pharmaceutical

Figure 12-2. General approach to developing a toxicity profile for pharmaceutical agents. Figure 12-2. General approach to developing a toxicity profile for pharmaceutical agents.
Toxicity testing of biopharmaceuticals is highly dependent on species specificity. Every program could be different in the type of studies that are needed to support safety assessment (i.e., case-by-case approach). If the biopharmaceuti-cal cross-reacts with the rodent target, then general toxicity tests can be conducted in two species similar to what is done with pharmaceuticals. If the... [Pg.353]


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General Approach

Toxicity, general

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