Total analysis system membrane

Jo, B., Moorthy, J., Beebe, D., Polymer microfluidic valves, membranes and coatings. Micro Total Analysis Systems, Proceedings of the 4th iTAS Symposium, Enschede, Netherlands, May 14-18, 2000, 335-338. 

For the past 10 to 15 years, semipermeable membranes have been utilized in microfluidics [8]. The concept of a micro total analysis system (jxTAS) was introduced by... 

The array ot 400 individually addressable electiodes allows an imaging of the distnbution of some further analytes in amperometiic mode Moreover it may be used for pattern recognition experiments Both arrays modified by any analyte-selective membrane can be used as chemical sensors or biosensois in micio total analysis systems... 

In this work, we have approaehed the understanding of proton transport with two tasks. In the first task, deseribed above, we have sought to identify the moleeular-level stmeture of PFSA membranes and their relevant interfaees as a funetion of water content and polymer architecture. In the second task, described in this Section, we explain our efforts to model and quantify proton transport in these membranes and interfaces and their dependence on water content and polymer architecture. As in the task I, the tool employed is molecular dynamics (MD) simulation. A non-reactive algorithm is sufficient to generate the morphology of the membrane and its interfaces. It is also capable of providing some information about transport in the system such as diffusivities of water and the vehicular component of the proton diffusivity. Moreover, analysis of the hydration of hydronium ion provides indirect information about the structural component of proton diffusion, but a direct measure of the total proton diffusivity is beyond the capabilities of a non-reactive MD simulation. Therefore, in the task II, we develop and implement a reactive molecular dynamics algorithm that will lead to direct measurement of the total proton diffusivity. As the work is an active field, we report the work to date. 

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