Tobacco sniffing

Ingestion of nicotine is an ancient and widespread practice. Native North, Central, and South Americans have smoked, chewed, sniffed, and drank tobacco preparations for thousands of years. It was used in religious and ceremonial rituals, as a medication, and to suppress hunger. The word tobacco is derived from tobaga pipes used by Central American natives. 

In former times, chewing or sniffing tobacco were quite popular, further illustrating that nicotine can be taken up across membrane barriers. 

Snuff is taken through the mouth or the nose. Moist snuff is fmely cut tobacco plus flavorings, with a moisture content of up to 50%. It is placed in the cheek. Dry snuff has a moisture content of less than 10% and may have flavorings. It may be sniffed through the nose, placed behind the lower Up, or in the cheek. Oriental snuff is about 50% heated calcium carbonate and calcium phosphate with some powdered cuttle-fish bone. In southern Africa, snuff is made from powdered tobacco leaves, plant ash, and sometimes oils, lemon juice, and herbs. In the United States, dipping refers to the ingestion use of snuff. 

Oral sniffed inhalation by smoking (sprinkled on marijuana, parsley, tobacco, or other substance that can be smoked) intravenous injection... 

Tobacco Nicotiana tabacum), a native plant of the Americas, has been cultivated since 5000-3000 BC and was in widespread use when Christopher Columbus arrived in the New World in 1492 (Musk and de Klerk 2003) (Figure 4.7). Tobacco was sniffed, chewed, eaten, drunk, applied topically to kill parasites and used in eye drops and enemas. The act of smoking tobacco appears to have evolved from snuffing and is currently the most... 

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