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Tissue growth factor angiogenesis

Furthermore, it was indicated that miR-17-19b cluster included in miR-17-92 cluster inhibited apoptotic cell death, and accelerated c-Myc-induced lymphomagenesis in mice reconstituted with miR-17-19b cluster-over-expressed haematopoietic stem cells (43). In addition, the miR-17-92 cluster has been reported to augment angiogenesis in vivo by down-regulation of anti-angiogenic thrombospondin-1 and coimective tissue growth factor in Ras-transformed colonoc Tes (45). [Pg.50]

The antibody brings about its effect by inhibiting angiogenesis (the formation of new blood vessels), a process required to support tumour growth. Specifically, the antibody binds human vascular endothelial growth factor. This prevents the latter from binding to its cell surface receptor, a process central to triggering new blood vessel formation in both normal and diseased tissue. [Pg.394]

See other pages where Tissue growth factor angiogenesis is mentioned: [Pg.80]    [Pg.193]    [Pg.154]    [Pg.328]    [Pg.342]    [Pg.530]    [Pg.86]    [Pg.217]    [Pg.234]    [Pg.235]    [Pg.243]    [Pg.243]    [Pg.338]    [Pg.237]    [Pg.31]    [Pg.134]    [Pg.457]    [Pg.570]    [Pg.1902]    [Pg.365]    [Pg.24]    [Pg.62]    [Pg.40]    [Pg.110]    [Pg.353]    [Pg.244]    [Pg.340]    [Pg.365]    [Pg.367]    [Pg.398]    [Pg.401]    [Pg.410]    [Pg.410]    [Pg.447]    [Pg.148]    [Pg.285]    [Pg.286]    [Pg.287]    [Pg.289]    [Pg.316]    [Pg.199]    [Pg.484]    [Pg.204]    [Pg.131]    [Pg.199]    [Pg.541]    [Pg.171]   
See also in sourсe #XX -- [ Pg.340 ]



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