Tibiofemoral joint

The tibiofemoral joint is mainly a joint with two degrees of freedom. The first degree of freedom allows movements of flexion and extension in the sagittal plane. The axis of rotation lies perpendicular to the... 

The injection of CxcU or Cxcl2 into the tibiofemoral joint of mice leads to rapid migration of significant numbers of neutrophils into the knee. The injection of 100 ng of CxcU in the joint is optimal to induce recruitment of neutrophils and cells can be easily recovered from the joint cavity 3 h after injection of the chemokine. Injection of human CXCL8 also induces the recruitment of neutrophils, albeit the dose necessary to cause recruitment is higher, approximately 1 j. /joint. Steps for the intra-articular injection of the chemokine and details for the evaluation of cells are given below. 

As the tibiofemoral joint is a very small cavity, it is useful to adapt the syringe in order to facilitate the injection into the joint and to avoid missing the cavity. 

Figure 4 Procedure for cell recovery from the tibiofemoral joint. Remove the skin under the knee (A). Cut the patellar tendon carefully with a delicate scissor (B). Open the articular cavity using tweezers (C). Dashed line can be removed for enzymatic assays (D). Wash the joint cavity with diluent (5 pL, 2x) to recover accumulated cells.

Activity Reference Patel lo-femoral joint Tibiofemoral Joint (compression) Tibiofemoral Joint (anterior shear) ... 

Which of the following daily activities can produce the greatest compression forces in the tibiofemoral joint ... 

The forces exerted between the femur and patella and between femur and tibia depend mainly on the geometry of the muscles that cross the loiee. For maximum isometric extension peak forces transmitted to the patellofemoral and tibiofemoral joints are around 11,000 N and 6500 N, respectively (i.e., 15.7 and 9.3 times body weight, respectively) (Fig. 6.27). As the knee moves faster during isokinetic extension exercise, joint-contact forces decrease in dire proportion to the drop in quadriceps force (T. Yanagawa and M. G. Pandy, unpublished results). 

Morimoto Y, Ferretti M, Ekdahl M et al (2009) Tibiofemoral joint contact area and pressure after single- and double-bundle anterior cruciate ligament reconstruction. Arthroscopy 25 62-69... 

Hashemi J, Chandrashekar N, Gill B, Beynnon BD, Slauterbeck JR, Schutt RC Jr, Mansouri H, Dabezies E (2008) The geometry of the tibial plateau and its influence on the biomechanics of the tibiofemoral joint. J Bone Joint Surg Am 90 2724-2734... 

The largest of these joints, the tibiofemoral joint, obtains its stabihty from the conformity of its bony structures, the medial and lateral menisci, the medial and collateral ligaments, the anterior and posterior cruciate ligaments and the joint capsule. 

During walking, the tibiofemoral joint has 2-4 times the body weight across it, whereas the patellofemoral joint has only 0.5 times body weight. 

Impact Load and Mechanical Respond of Tibiofemoral Joint... 

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