Thyroid Antithyroid Drugs

List the principal drugs used in the treatment of hypothyroidism. [Pg.336]

List the principal drugs used in the treatment of hyperthyroidism and compare the onset and duration of their action. [Pg.336]

Sketch the biochemical pathway for thyroid hormone synthesis and release and indicate the sites of action of antithyroid drugs. [Pg.336]

Describe the major toxicides of thyroxine and the antithyroid drugs. [Pg.336]

Iodide concentrations higher than normal inhibit iodination of tyrosine, an effect that is useful in the treatment of thyroid disease. Inadequate iodine intake results in diffuse enlargement of the thyroid (goiter). [Pg.337]

Chapter 37 Hypothalamic Pituitary Hormones Chapter 38 Thyroid Antithyroid Drugs... [Pg.7]

Basic and Clinical Pharmacology > Chapter 38. Thyroid Antithyroid Drugs > ... [Pg.853]

CLINICAL PHARMACOLOGY OF THYROID ANTITHYROID DRUGS Hypothyroidism... [Pg.865]

AccessMedicine Print Chapter 38. Thyroid Antithyroid Drugs Oral 5, 25, 50 meg tablets Parenteral 10 mcg/mL Liotrix [a 4 1 ratio of T4 T3] (Thyrolar)... [Pg.872]

Excessive catecholamine action is an important aspect of the pathophysiology of hyperthyroidism, especially in relation to the heart (see Chapter 38 Thyroid Antithyroid Drugs). The Bantagonists have salutary effects in this condition. These beneficial effects presumably relate to blockade of adrenoceptors and perhaps in part to the inhibition of peripheral conversion of thyroxine to triiodothyronine. The latter action may vary from one Bantagonist to another. Propranolol has been used extensively in patients with thyroid storm (severe hyperthyroidism) it is used cautiously in patients with this condition to control supraventricular tachycardias that often precipitate heart failure. [Pg.220]

Treatment of metastatic differentiated thyroid cancer requires the administration of large doses of 131I (30-200 mCi) in the presence of persistently high serum levels of TSH (see Chapter 38 Thyroid Antithyroid Drugs). Patients must withdraw from thyroid hormone replacement in order to achieve this. For treatment purposes, thyrotropin alpha administration cannot substitute for thyroid hormone withdrawal. [Pg.860]

He flJiH npoflaacM CKaH m fleacaBio-KOHBepcMH MyCAHfl 3 poHT.py >— thyroid Antithyroid drugs / 339... [Pg.339]

Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...