Thymidine pyrophosphate , enzymic synthesis

The more-common 2-acetamido-2-deoxyhexoses have not been found as thymidine 5 -pyrophosphate derivatives. Nevertheless, the enzymic synthesis of thymidine 5 -(2-acetamido-2-deoxy-a-D-gluco-pyranosyl pyrophosphate) and -(2-acetamido-2-deoxy-a-D-galactopy-ranosyl pyrophosphate) has been achieved with enzyme preparations from Pseudomonas aeruginosa,116 Azotobacter vinelandii,52 and gastric mucosa.117... 

Cell-free extracts of the same micro-organism are able to catalyze the formation of the complete L-rhamnolipid from thymidine 5-(L-rhamno-pyranosyl pyrophosphate) and f3-hydroxydecanoyl)-Coenzyme A. It is clear that several enzymic steps must be involved in this synthesis. 

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