Thiol ligands reactions

Other excellent results have been reported by Kang et al. for the addition of ZnEt2 to aldehydes by using chiral cyclic amino thiol ligands depicted in Scheme 3.7. A total enantioselectivity was obtained when (lR,25)-l-phenyl-2-piperidinopropane-1-thiol was used as the ligand in the reactions of substituted benzaldehydes. However, -hexanal and traw -cinnamaldehyde could only be... 

On the other hand, novel diastereomeric p-amino thiol ligands possessing an isoquinuclidine skeleton have been readily prepared by Hongo et al. via imino-Diels-Alder reactions.As shown in Scheme 3.15, when applied to the enantioselective addition of ZnEt2 to various aldehydes, one of these ligands afforded the products with high enantioselectivities of up to 94% ee. 

Scheme 3.9 Thiol ligands used in the ligand exchange reaction with 1.5 nm PPh3-stabilized Au NPs.

The high affinity of bismuth for charged sulfur ligands results in the ready generation of bismuth thiolates from a range of bismuth salts and an appropriate thiol, although reaction of Na(Li)SR with Bids or of BiPh3 with RSH have also been Examples are... 

Physiological thiol ligands such as glutathione (GSH) also drive the displacement of phosphine (equation 12). The oxidant in equation 11 can be either molecular oxygen (equation 13a) or the albumin disulfide (equation 13b), yet the reaction proceeds at a similar rate and to about the same extent aerobically or anaerobically. S Since free O2 is not present in serum, it is likely that disulfide bonds are the in vivo oxidants. ... 

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