Thioglycosides in Block Synthesis of Oligosaccharides

The synthesis is an excellent example of the use of thioglycosides as glycosyl donors in the block synthesis of complex oligosaccharides as well as the use of partial glycosylation of diols to achieve short paths to the target. 

Thioglycosides containing free OH groups readily tolerate silver triflate-pro-moted glycosylations with glycosyl bromides and chlorides, and also tin(II) chloride-silver perchlorate-activated glycosylation, and several examples have 

Thioglycosides can also be used as acceptors in glycosylation with tri-chloroacetimidates.18 

---