Toremifene Thiazides

Aromatase inhibitors (including anastrozole, letrozole, aminoglutethimide, exemestane, formestane, testolactone), selective estrogen receptor modulators—SERMs (including raloxifene, tamoxifen, toremifene), clomiphene, cyclofenil, fulvestrant Diuretics, amiloride, bumetanide, canrenone, chlorthalidone, etacrynic acid, furosemide, indapamide, metolazone, spironolactone, thiazides, triamterene... 

THIAZIDES HORMONES AND HORMONE ANTAGONISTS -TOREMIFENE Risk of hypercalcaemia Additive effect Monitor calcium levels closely. Warn patients about the symptoms of hypercalcaemia... 

Based on theoretical considerations, the manufacturers advise care when toremifene is given with thiazides and with CYP3A inhibitors such as erythromycin, ketoconazole, and troleandomy-cin. 

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