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Therapeutic Targeting of the CXCR3 Receptor

Chemokine Receptors as Drug Targets. Edited by Maitine J. Smit, Sergio A. Lira, and Rob Leurs Copyri t 2011 WILEY-VCH Verlag GmbH Co. KGaA, Weinheim ISBN 978-3-527-32118-6 [Pg.301]

The CXCR3 chemokine receptor and its ligands may also prove to be important targets for therapeutic interventions. Because of its role in immune surveillance and T-cell function, CXCR3 is implicated as a mediator of acute allograft rejection (Hancock et al, 2000) and complications in... [Pg.66]

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Targeted therapeutics

Targets targeted therapeutics

The target

Therapeutic targeting

Therapeutic targets