Thebaine nitration

Thallium metal, 24 627—629 Thallium nitrates, 24 633 Thallium organometallics, 24 633—635 Thallium oxides, 24 632—633 Thallium poisonings, 24 637, 638-639 Thallium stress test, 24 629 Thallium sulfates, 24 628, 633 Thaumatin, 72 43, 24 241-242 Thaumatin II, 24 242 Theaspiranes, 24 572 Thebaine, 2 89 Thenardite, 22 863, 5 785t Thenoyltrifluoroacetone molecular formula, 5 712t Theobroma cacao, 6 350 Theobromine, 2 105-106... 

During a study of the nitration of thebaine with tetranitromethane,(287) the unusual epoxide 183 was isolated when the nitration was performed in the presence of air. In establishing the structure of 183, two products (210a and b) oxygenated at C-10 were isolated. 

Column Partisll 6 urn (250x4.6 mm ID), mobile phase methanol - 2 M amnonia - 1 M aimionium nitrate (27 2 1), flow rate 1 ml/min, detection UV 278 nm. A. Opium sample, peaks 1, nos-capine 2, thebaine 3, codeine 4, morphine. B. "Chinese Heroin" sample, peaks 1, caffeine 2, heroin 3, Oracetylmorphine 4, morphine 5, strychnine. 

Oxidation of desmethoxydihydrosinomenine with silver nitrate results in linking of two molecules in the l T-position to give bis-1 T-desmethoxydihydrosinomenine, which can be degraded to bis-1 T-desmethoxydihydrosinomenine methine, bis-1 1 -desmethoxydihydrosinomenine dihydromethine, bis-1 T - 9 10-dehydro-( —)-thebenone, and bis-1 l -(—)-thebenone, all of which can be racemized with the corresponding compound prepared from the thebaine series [49]. 

Allen RM, Kirby GW, McDougall DJ (1981) The nitration of thebaine with tetranitromethane. J Chem Soc Perkin Trans I 26 1143-1147... 

Narcotine, thebaine, codeine and morphine present as the major components in an opium sample Adsorption Partisil Methanol/2N ammonium hydroxide/IN ammonium nitrate (27 2 1)... 

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