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The SCF E3 Superfamily

The SCF and SCF-like complexes are multi-subunit RING-type E3s that represent the largest E3 family knotvn to date. This superfamily of E3s are involved in regulating cell-cycle progression, signal transduction pathways, transcriptional control, and multiple aspects of cell growth and development (reviewed in Ref. [50]). All members of this E3 superfamily contain two basic components, a member of the cullin protein family and a RING-domain protein. The cullin subumt serves as the [Pg.167]


See other pages where The SCF E3 Superfamily is mentioned: [Pg.167]    [Pg.171]    [Pg.173]    [Pg.175]    [Pg.177]    [Pg.167]    [Pg.171]    [Pg.173]    [Pg.175]    [Pg.177]    [Pg.339]    [Pg.192]    [Pg.168]    [Pg.98]   


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SCF

SCFs

Superfamily

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