The 10 per cent rule for cure rates

It has been relatively common practice, historically, to use a A of 10 per cent for cure rates. 

CPMP (1999) Note for Guidance on Clinical Evaluation of New Vaccines  

CPMP (2003) Note for Guidance on Evaluation of MedianaI Products Indicated for Treatments of Bacterial Infections  

There are one or two other specific therapeutic settings where there is more guidance on the choice of A. For example  

CPMP (2003) Points to Consider on the Clinical Development of Fibrinolytic Medicinal Products in the Treatment of Patients with ST Segment Evaluation Acute Myocardial Infarction (STEMI)  

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