THE MULTIPHASE ANTIVIRAL STATE HYPOTHESIS

Extract prepared by the micrococcal nuclease method (34) or by 30 min pre-incubation with an energy source (23)9 Rabbit liver tRRA used at 8 jxg/ml. 35s-methionine incorporation measured 60 min after mRNA. 

We thank Dr. D. Shafritz for gifts of eIF-2. The excellent assistance of Ms. P. Federman and H. Berissi is gratefully acknowledged. Work supported by NCRD (Israel) and GSF (MUnchen, Germany). 

ZILBERSTEIN, A., SCHMIDT, A. and REVEL, M. Nature (London), submitted. 

SCHMIDT, A., ZILBERSTEIN, A., SHULMAH, L., EEDEEMAH, P., BERISSI, H. ajid EiTVEL, M. PEBS Letts, in press. 

and DUDOCK, B. Colloques INSEEM In vitro transcription and translation of viral genomes, Haenni, A. and Beaud, G. eds., (1975), Vol. 47 pp. 397-406, INSEEM Paris. 

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