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The Human Genome

ITS Sequence tagged site. A short DNA sequence that occurs just once in the human genome and whose location and base sequence are known... [Pg.570]

The human genome sequence has been called the book of life and more modestly a tool box and an instruction manual Regardless of what we call it it promises a future characterized by a fuller understanding of human biology and medical science... [Pg.1183]

Section 28 15 A rough draft of the sequence of nucleotides that make up the human genome has been completed There is every reason to believe that the increased knowledge of human biology it offers will dramatically affect the practice of medicine... [Pg.1189]

Biotechnology. Particular attention must be paid to the detection of DNA in all finished biotechnology products because of the possibiUty that such DNA could be incorporated into the human genome and thus become a potential oncogene. The absence of DNA at the picogram-per-dose level should be demonstrated in order to assure the safety of biotechnology products (157). [Pg.251]

SK Burley, SC Almo, JB Bonano, M Capel, MR Chance, T Gaasterland, D Lm, A Sail, EW Studier, S Swammathan. Structural genomics Beyond the human genome project. Nat Genet 23 151-157, 1999. [Pg.312]

The Human Genome Project is also vital to medicine. A number of human diseases have been traced to genetic defects, whose positions within the human genome have been identified. Among these are... [Pg.412]

The abundance of many protein kinases in cells is an indication of the great importance of protein phosphorylation in cellular regulation. Exactly 113 protein kinase genes have been recognized in yeast, and it is estimated that the human genome encodes more than 1000 different protein kinases. Tyrosine kinases (protein kinases that phosphorylate Tyr residues) occur only in multicellular organisms (yeast has no tyrosine kinases). Tyrosine kinases are components of signaling pathways involved in cell-cell communication (see Chapter 34). [Pg.466]

Currently there are drugs for only a fraction of the draggable targets present in the human genome. [Pg.18]

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Human genome

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