The Activity-Stability Parameterization of Homogeneous Green Oxidation Catalysts

The Activity-Stability Parameterization of Homogeneous Green Oxidation Catalysts 

The progress of Green Chemistry impacts the established scenarios for the chemical industry (98,99). Future catalysts will likely become more enzyme-like in the sense that they will more efficiently balance the properties of effectiveness and fragility. An overarching environmental consideration holds a synthetic catalyst should simply go away by some mechanism when its work is done. Nature has developed enzymes with limited lifetimes. After their task is completed, their constituent molecules and atoms become recyclable to serve as useful resources for the 

The rate constants of kn and kx obtained using Eq. (24) reveal that (i) the activity of Fem-TAMLs in bleaching Safranine O (k ) increases more than 10-fold when the tail ethyl groups of la are replaced by fluorine atoms in lk. The rate constant kn for lk equals l(rM 1s 1 at 25°C, a value that corresponds to those found for the reactivity of horseradish peroxidase Compound II 

(24) can be rearranged to a form (Eq. (25)) that describes a relative conversion of substrate (A /A0) as a function of time (52). Eq. (25) is convenient for simulating the catalyst performance using the current model. Theoretical predictions can be compared with the experimental data. Eq. (25) eliminates the illusion that Fem-TAML-catalyzed bleaching is always incomplete as in Fig. 17. 

Support for the mechanistic concept is a match between the experimental and calculated data using known k, and ku. 

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