Thalitone

Tabiets 15, 25, 50, and 100 mg (Rx) Various, Hygroton (Rhone-Poulenc Rorer), Thalitone (Horus Therapeutics)... 

Edema - Initiate therapy with 50 to 100 mg Thalitone, 30 to 60 mg) daily, or 100 mg Thalitone, 60 mg) on alternate days. Some patients may require 150 or 200 mg Thalitone, 90 to 120 mg) at these intervals, or 120 mg Thalitone daily. However, dosages above this level do not usually create a greater response. 

Hypertension - Initiate therapy with a single dose of 25 mg/day Thalitone, 15 mg). If response is insufficient after a suitable trial, increase to 50 mg Thalitone, increase from 30 to 50 mg). For additional control, increase dosage to 100 mg once daily (except Thalitone), or add a second antihypertensive. 

Chlorthalidone (generic, Hygroton, Thalitone, combination drugs)... 

Oral 250, 500 mg tablets 250 mg/5 mL oral suspension Parenteral 500 mg for injection Chlorthalidone(generic, Thalitone, combination drugs) Oral 15, 25, 50, 100 mg tablets Demeclocycline(Declomycin)... 

Hypertol Igroton Tenoretic (AstraZeneca) Thalidone Thalitone... 

Tesmel chloroquine Aureomicina, Aureomycin Combipres, Higroton, Hydro-Long, Hygroton, Hypertol, Igroton, Tenoretic, Thalidone, Thalitone,... 

Chlorthalidone has a long duration of action (48-72 hours) (see Table 27.3 for its other pharmacokinetic properties). Although quinethazone and metolazone are administered daily, chlorthalidone may be administered in doses of 25 to 100 mg three times a week. When chlorthalidone is formulated with the excipient povidone, the product. Thalitone. has greater bioavailability (>90%) and reaches peak plasma concentrations in a shorter time compared with its other products. Similar to the quinazolinones. it also is extensively bound to carbonic anhydrase in the erythrocytes. Chlorthalidone-induced effects on urine content and side effects are similar to those induced by thiazide diuretics. 

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