Tetrazole, synthesis from aminotetrazole

The high nitrogen content and the endothermic nature of the tetrazole ring lends itself to the synthesis of energetic materials. Compounds such as -H tetrazole and 5-aminotetrazole can be used as nucleophiles to incorporate the tetrazole ring into other molecules. 5-Aminotetrazole is synthesized from the reaction of dicyandiamide with sodium azide in hydrochloric acid. 

Synthesis of tetrazole compds from acid nitriles) 3)R.M.Herbst et al, JOC,16,13SM9(195l) CA 45, 6629-31(1951) (18 refs) (Prepn of various 1— alkyl—5—aminotetrazoles by the interaction of aikyicyanides with hydrazoic acid in benzene so in in the presence of a coned acid some props of... 

Synthesis from tetrazole precursors was reported [60LA159 79JCS(P1)3085], according to which 5-aminotetrazole (388) was cyclo-condensed with 2-hydroxymethylenecyclohexanone to give tetrazolo [l,5-a]quinazoline (389) instead of the expected tetrazolo[5,l-fc] quinazoline (390). 

Many Tetrazole Drugs Made from 5-Aminotetrazole Analysis Synthesis... 

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