2 ’ ,4 ’ ,5 ’ ,7 ’ -Tetraiodofluorescein

Fig. 3.167. Structures of 2, 4, 5 -triiodofluorescein, 2, 4, 7 -triiodofluorescein, and 2, 4, 5, 7 -tetraiodofluorescein (major components FD C Red No. 3). Reprinted with permission from L. Evans III [203],...

Jennings AS, Schwartz SL, Balter NJ, Gardner D, Witorsch RJ (1990) Effects of oral erythro-sine (2, 4, 5, 7 -tetraiodofluorescein) on the pituitary-thyroid axis in rats. Toxicol Appl Pharmacol 103(3) 549-556... 

Rose Bengal (4,5,6,7-tetrachloro-2 ,4 ,5 ,7 -tetraiodofluorescein disodium salt RB), Polypepton fine granules, magnesium sulfate heptahydrate, agar powder were purchased from Wako Pure Chemical Industries Co., Ltd. (Osaka, Japan) and yeast extract from Kanto Kagaku Co., Ltd. (Tokyo, Japan). 

CARBOXYPHENYl)-6-HYDROXY-2,4,5,7-TETRAIODO-3-ISOXANTHONE CILEFAPINKB D CREDNO. 3 DOLKWAL ERYTHROSINE DYE FD C RED NO. 3 ERYTHROSIN MAPLE ERYTHROSINE 2 4, 5, 7 -TETRAIODOFLUORESCEIN, DISODIUM SALT TETRAIODOFLUORESCEIN SODIUM SALT USACERT RED NO. 3... 

Tetrahydroxytitanium. See Titanium hydroxide 2,2-6,6-Tetra (hyroxymethyl)-4-oxaheptan-1,7-diol. See Dipentaerythritol 2, 4, 5, 7 -Tetraiodofluorescein disodium salt. See FD C Red No. 3 Acid red 51 Tetraiodofluorescein sodium salt. See FD C Red No. 3 Acid red 51... 

Other Names Fluorescein, 2, 4, 5, 7 -tetraiodo-, disodium salt 1427 Red 1671 Red 2, 4, 5, 7 -Tetraiodofluorescein disodium salt 2,4,5,7-Tetraiodofluorescein disodium salt Acid Red 51 Aizen Erythrosine Aizen Food Red 3 C.l. 45430 C.I. Acid Red 51 C.l. Food Red 14 Calco-cid Erythrosine N Canacert Erythrosine BS Ceplac Cilefa Pink B D and C Red No. 3 D C Red No. 3 Dolkwal Erythrosine E 127 Edicol Supra Erythrosin AS Edicol Supra Erythrosine A Erythrosin Erythrosin B Erythrosin B sodium salt Erythrosin BS Erythrosine Erythrosine 3B Erythrosine B-EO Erythrosine BS Erythrosine Bluish Erythrosine Extra Erythrosine Extra Cone. A Export Erythrosine Extra Pure A Erythrosine I Erythrosine K-EO Erythrosine TB Erythrosine TB Extra Erythrosine extra bluish FD and C Red 3 FD and C Red No. 3 FD C Red No. 3 FDC Red 3 FDC Red 3 dye Food Color Red 3 Food Dye Red 3 Food Red 14 Food Red 3 Food Red No. 3 Hexacert Red No. 3 Hexacol Erythrosine BS Japan Red 3 Japan Red No. 3 Maple Erythrosine New Pink Bluish Geigy Red 1799 S 887 Synerid Tetraiodofluorescein sodium salt Usacert Red No. 3... 

The disodium salt of 2, 4, 5, 7 -tetraiodofluorescein, erythrosine, is listed by the Colour Index (1971) as Cl 45430/Acid Red 51 and Cl 45430 1/Pigment Red 172 as the aluminium salt. It was discovered by Kussmaul in 1876 (Colour Index, 1971). Sources such as Weber (1923) and Heaton (1928) say that, along with eosin and related dye compounds, it was used to form lake pigments such as that commonly known as geranium lake (qq.v.). 

Figure 4.21 Inhibition of chlorpromazine-induced haemolysis by fluorescein derivatives (5x10" m). O, no inhibitor A, 2, 4, 5, 7 -tetrachlorofluorescein , 2, 4, 5, 7 -tetrabromofluorescein (eosin Y) , 2 4, 5, 7 -tetraiodofluorescein (erythrosin B) and , 4, 5 -dibromo-2, 7 -dinitrofluorescein (eosin B). From Baur [170] with permission.

---