Tetraethylene glycol bis

Another interesting application of thiadiazole chemistry is the synthesis of thiacrown ether. To this end, the precursor thiadiazole is treated with K2CO3 in the presence of 1,11-dichloro-3,6,9-trioxaundecane to give l,ll-bis(5-hydroxybenzofuran-2-sulfanyl)-3,6,9-trioxaundecane, which can be transformed into thiacrown ether 110 by treatment with tetraethylene glycol bis-tosylate and bases <00T3933>. 

Tetraethylene glycol dimethacrylate (TEGDMA), 43 733, 734 Tetraethylene glycol bis(allyl carbonate) properties of, 2 253t T etr aethylenepentamine physical properties, 8 486t... 

Table I summarizes the results obtained the actual gel-point conversions increased with an increase in the molecular weight of monomer. On the contrary, the discrepancy between actual and theoretical gel-point conversions was notably reduced from DAP to tetraethylene glycol bis(allyl phthalate)(n=3). This may be ascribed to the reduction of excluded volume effects on crosslinking (16,17) with the increase of the molecular weight of monomers, although the details of excluded volume effects on crosslinking will be discussed elsewhere.

Tetrabenzoperaza-crown-4 cyclophanes (biphenyl), table, lli Tetrabenzoperaza-crown-4 cyclophanes (miscellaneous), table, 734 Tetrabenzoperaza-crown-4 cyclophanes (tetrakis-p-phenylenyl), table, 726 Tetrabenzoperaza-crown-4 cyclophanes (tetrakis-p-xylyenyl), table, 731 Tetraethylene glycol bis(3-butenyl)-substituted, 38 chiral-substituted, 38 dichloride derivative, 179 diiodide derivative, 179, 184 tetramethyl-substituted, 38 Tetraethylenepentaamine, pertosylatcd, 49 Tetraglycolic acid, 112 Tetrahydro-l,4-diazepine, 93, 543 Tetrahydroazepine, 94 iV,A(Af iV -Tetrakis(2-hydroxyethyl)-ethylenediamine, 182... 

At around maximum yields.Determined by GLC, using tetraethylene glycol bis-p-ethylphenyl ether as an internal standard. 

The use of imines as the dynamic covalent bond significantly augmented the versatility of the thermodynamic approach toward the formation of interlocked systems. Stoddart et al. reported on the synthesis of [2]rolaxanes by the clipping protocol, in which a dialdehyde was used to clip the macrocycle under thermodynamically controlled conditions (Figure 6). In this system, the driving force for the formation of rotaxane 10 is the stabilizing interaction between ammonium ions and crown ethers, which was widely exploited by Stoddart and coworkers. In the first instance, a library of macrocyclic and linear compounds was prepared on condensation of tetraethylene glycol bis(2-aminophenyl)ether 6 and 2,6-diformylpyridine 7. 

At about the same time, Vogtle and Frensch reported the synthesis of a similar bis-crown based on the papaverine nucleus. This synthesis also was executed in the Williamson fashion using doubly-demethylated papaverine and tetraethylene glycol dichloride. The base, if used, was not specified but it was noted that the high dilution technique was not used. It was presumed that the major product was 10, shown below, but there was also evidence of other components, presumably 11 and 12. 

Tomoi and coworkers adopted a somewhat more direct approach in their synthesis of 16-crown-5 derivatives bearing a single alkenyl residue. They hoped to obtain precursors to polymers which could be used as phase transfer catalysts. In this approach I,I-bis-chloromethylethylene (a-chloromethallyl chloride) was allowed to react with the dianion of tetraethylene glycol (NaH/THF). By this method, methylene-16-crown-5 could be isolated in 66% yield after vacuum distillation. Ozonolysis led, in almost quantitative yield, to the formation of oxo-16-crown-5 as shown in Eq. (3.38). These authors prepared a number of other, closely related species by similar methods. 

Using the same versatile modular synthetic strategy, the same group developed biotinylated bi- (438) and tetra-antennary (439) mannosylated glycoconjugates to capture and detect E. coli cells, and compared the relative capturing ability of these molecules to commercial polyclonal antibodies (Fig. 47).318 Instead of aliphatic spacers, tetraethylene glycol linkers were used to diminish nonspecific binding and to impart flexibility for a better fit in the active sites. 

All maleimides were synthesized according to standard procedures.16 Maleic anhydride, dimethyl maleate, and diethyl fiimarate were purchased from Aldrich Chemical Co. and used as received. 1,4-Cyclohexanedimethanol divinyl ether (CHVE) and tetraethylene glycol divinyl ether (CHVE) were used as received from International Speciality Products. Bis(4-vinyloxybutyl) isophthalate (IPDBVE) and bis(vinyloxybutyl)succinate (SEGDVE) were obtained from Allied-Signal and used without further purification. All acrylates were used as received from either Aldrich Chemical Co. or Scientific Polymer Products. 2,2-Dimethoxy-2-phenylacetophenone (DMAP) was used as received from Ciba Specialty Chemicals. 

A base-promoted reaction between L-threitol and tetraethylene glycol di-tosylate afforded (165) the chiral bis(15-ctown-5) derivative l-146 as well as the trans-fused bicyclic system l-147 containing 15-crown-5 and 17-crown-5 rings. These constitutional isomers, which were separated chromatographically, were characterized by preparing l-147 unequivocally by a stepwise route from 2,3-O-isopropylidene-L-threitol. 

TETRAETHYLENE GLYCOL Hi-Dry, Bis-[2-(2-hydroxy-etlioxy)ethyl ether, 3,6,9-Trioxaundecan-l,U-diol NL 1 1 0... 

Synthesized (Fig. 28) in 32% yield [51,52] starting from 1,5-dihydroxy-naphthalene, the macrocyclic polyether 20 contains a 1,5-dioxynaphthalene unit and a bis(methanol)TTF ring system, linked in a cyclic fashion by two tetraethylene glycol chains. When this macrocyclic polyether was reacted with the precursors to CBPQT4+, the resulting [2]catenane 214+ was formed in 23% yield. 

Krakowiak and Bradshaw (1991) have observed that the reaction of certain diamines with the diiodide derivative of tetraethylene glycol gave the bis(aza-12-crown-4)s as by-products in the one-step synthesis of cryptands (method D-8). More work needs to be done on this interesting new one-step synthesis... 

EINECS 242-149-6 Flexol 4GO Hexanoic acid, 2-ethyl-, oxybis(2,1-ethyldiyloxy-2,1-ethanediyl)ester Hexanoic acid, 2-ethyl-, diester with tetraethylene glycol Plasticizer 4GO Polyethylene glycol 200 di(2-ethylhexoate) TegMeR 804 Tetraethylene glycol di(2-ethylhexoate) 3,6,9-Trioxaundecamethylene bis(2-ethylhexanoate). 

BRN 2011337 EINECS 274-829-3 Heptanoic acid, oxy-bis(2,1-ethanediyloxy-2,1-ethanediyl) ester Oxybis-(eth-ane-2,1-diyloxyethane-2,1-diyl) bisheptanoate Tegdh Tetraethylene glycol diheptanoate Tetraethylene glycol di-n-heptanoate. 

Photochemical cycloaddition of dimethyl fumarate and dimethyl maleate to the psoralen (15) has been reported. The adducts formed are presumed to be of the (2+2)-type illustrated by (16) where addition to the furan ring has occurred. The photodimerization of a,to-bis(4-methylcoumarin)tetraethylene glycol is re-giospecific and only the syn head-to-tail dimer is formed. ... 

Pyrido-18-crown-6 was prepared ( 30% yield) by reaction of 2,6-bis(hydroxymethyl)pyridine with potassium f-butoxide and tetraethylene glycol in (40 1) THF H20 <74JA68n>- A similar strategy was used (see Section 9.31.4) to prepare a bis(pyrido)tetrathia-24-crown-8 derivative. 

CAS 112-60-7 25322-68-3 (generic) EINECS/ELINCS 203-989-9 Synonyms Bis [2-(2-hydroxyethoxy) ethyl] ether 2-[2-(2-(2-Hydroxyeth-oxy) ethoxy) ethoxy] ethanol Macrogol 200 2,2 -[Oxybis (2,1-ethanediyloxy)] bisethanol 2,2 -(Oxybis (ethyleneoxy)) diethanol PEG 200 POE (4) TEG Tetraethylene glycol Tetraglycol Definition Polymer of ethylene oxide Empirical CiHuOs Formula H(OCH2CH2),OH... 

CH3-0-(CH2CH2-0)4-CH3 Tetraethylene glycol dimethyl ether Bis(2-(2-methoxyethoxy) ethyl) ether Dimethoxytetraethylene glycol 2,5,8,11,14-pentaoxapentadecane (143-24-8)... 

Trioxaundecyl) bis-3-(dodecylthio) propionate. See 3-(Dodecylthio) propionic acid/tetraethylene glycol diester... 

D.-J. Lee, J. Hassoun, S. Panero, Y.-K. Sun, B. Scrosati, Electrochem. Commun. 2012, 14, 43-46. A tetraethylene glycol dimethylether-lithium bis(oxalate)borate (TEGDME-LiBOB) electrolyte for advanced lithium ion batteries. 

TEGDME (tetraethylene glycol dimethyl ether, tetraglyme), ionic liquids, and solid electrolyte were proposed as candidate electrolyte. As a liquid electrolyte, ionic liquid may be a solution. 1-Ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide (EMI... 

Many amphiphiUc substances are able to form reversed micelles. Certainly, the most studied is sodium bis (2-ethylhexyl) sulfosuccinate (AOT) [6]. From this salt, other interesting surfactants able to form reversed micelles have been derived by simply changing the counterion [7]. Other frequently used surfactants are didodecyldimethylammonium bromide [8], benzyldimethylhexadecylam-monium chloride, lecithin [9], tetraethylene glycol monododecyl ether (C12E4) [10], decaglycerol dioleate [11], and dodecylpyridinium iodide [12],... 

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