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Tetraethylammonium organic cation transport

Organic cation transporters OCT1/2 tetraethylammonium (TEA), thiamine,... [Pg.259]

Our understanding of the organic ion secretory mechanisms derives essentially from investigations on a few transported compounds that are considered representative of other secreted organic ions. For organic anions the classical substrate is p-aminohippurate (PAH) whereas for organic cations classical substrates are tetraethylammonium (TEA) and Nj-methylnico-tinamide... [Pg.49]

Figure 6. Model of the organic cation tetraethylammonium transport in proximal tubule. Figure 6. Model of the organic cation tetraethylammonium transport in proximal tubule.
Transport mechanisms for organic cations have been investigated not only for the classical substrates, tetraethylammonium and Ni-methytnicotinamide, but also for a few other organic cations, mainly drugs. [Pg.33]

The administration of tetraethylammonium (TEA) and the organic anionic phenol-sufonphthalein (PSP) can be used as indices of cationic tubular transport systems (Klaassen and Plaa 1966). However, these tests are not included in general toxicity studies. Again, these tests require administration of the compound and carefully timed sample collections (Poutsiaka et al. 1962). [Pg.88]


See other pages where Tetraethylammonium organic cation transport is mentioned: [Pg.293]    [Pg.389]    [Pg.714]    [Pg.296]    [Pg.235]    [Pg.115]    [Pg.34]    [Pg.34]    [Pg.671]    [Pg.109]    [Pg.519]    [Pg.34]    [Pg.35]    [Pg.175]    [Pg.189]    [Pg.40]    [Pg.44]   
See also in sourсe #XX -- [ Pg.55 , Pg.56 , Pg.57 , Pg.58 ]

See also in sourсe #XX -- [ Pg.33 , Pg.34 , Pg.35 , Pg.36 ]




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